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next-generation ffpe proteomics
 

INTRODUCING SAPIENT'S

Next-Generation FFPE Proteomics

Revealing functional tumor biology from FFPE tissue – quantitatively, reproducibly, and at scale.

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The proteome, which defines target expression, pathway activation, post-translational signaling, and drug response, has remained largely inaccessible in FFPE samples... until now.

Our mass spectrometry-based FFPE workflows enable direct measure of 10,000+ protein groups in FFPE tissue & tumors.

 

Transform under-utilized FFPE tissue biorepositories into a new discovery source.

Go beyond genomic profiling and RNA sequencing to extract functional insights from FFPE tissue. From a single 5µm FFPE slide, Sapient delivers quantitative measures across thousands of proteins including 200+ oncogenes, 500+ approved drug targets, and 100+ pathways.

 

Confirm target engagement & pathway modulation to accelerate proof-of-mechanism.

Bridge translational gaps with protein-level insights into tumor signaling, immune activation, and pharmacodynamic effects, enabling correlation of pathway activation and clinical response.

 

Optimize patient selection precision.

Targeted, quantitative assays can be optimized to evaluate key protein targets within clinical FFPE samples, enabling early detection of pathway modulation to guide patient stratification and dose adjustments.

Multi-omic molecular mapping

Integrating FFPE Proteomics within our broader multi-omics workflows, we can reconstruct tumor biology from mutation to pathway activation, cell-type, and spatial localization.

ffpe mult-omics platform

Unlock new insights from existing FFPE tissue, today.

Let's discuss your programs & how we can deliver previously inaccessible protein data from your FFPE samples or ours.

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10421 Wateridge Circle, Suite 100
San Diego, CA 92121

858.290.7010

 

 

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