Happy spring! Take some time to explore emerging trends in precision drug development and The INsight most recently generated through multi-omics and dynamic biomarkers.

 

In this issue...

 
  • A pharmaceutical industry leader joins the Sapient team
  • Creating competitive advantages in the GLP-1 agonist market
  • Proteomics to advance protein degraders: a comprehensive approach
  • Mark your calendar for these key upcoming events
 

Sapient Appoints Jonathan Usuka, PhD, MBA as Chief Business Officer 

Dr. Usuka’s deep experience in the pharmaceutical industry spans more than 25 years, including business and scientific leadership roles at REALM IDx, McKinsey & Company, Celgene, and Roche. He brings a visionary perspective and practical understanding of how to apply data to accelerate biopharma R&D, and will be the driving force in helping our clients leverage Sapient's large-scale multi-omics lab and industry leading real-world data asset for clinical impact.

Science from Sapient: here's the latest

 
 

Metabolomics insights to speed development of GLP-1 therapies

Article: Learn how large-scale profiling of metabolite and lipid biomarkers can speed GLP-1 agonist time-to-market and drive competitive advantages via novel insights to enhance efficacy and safety.

 

Protein Degrader Proteomics for PROTACs and Molecular Glues

White Sheet: Explore methods optimized to screen thousands of protein degrader molecules for target efficiency and to deeply profile select degraders across cell lines, drugs, doses, and time points.

 

Advancing Clinical Biomarkers through Mass Spectrometry-based Discovery Proteomics

Webinar: What technology advances are now enabling accurate and robust measure of thousands of proteins and PTMs across thousands of individuals?

 

Subtyping, Predicting, and Treating CKD: Finding New Paths with Nontargeted Biomarker Discovery

Blog: See how biomarkers discovered via nontargeted approaches can elucidate unknown disease biology to guide therapeutic development.

 
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Promising advances at the 12th Alzheimer's and Parkinson's Drug Development Summit

It was great to attend this recent event in Boston and see firsthand just how quickly neurodegenerative therapeutics are advancing. While there is still much more to accomplish, breakthroughs are coming – and we are certain that dynamic biomarkers will be a critical part of the future of AD and PD therapies.

 

If you weren't at the conference but want to hear more about the discussions, we'd be happy to share our key takeaways. Click here to set up a time to connect.

 
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Discovery Europe 2024

May 22-23, 2024
Basel, Switzerland

 

Meet us at Booth 21 and join our talk on "Next-gen multi-omics to accelerate drug discovery and development" on 5/22. 

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ASMS 2024 &  eXceed

June 2-6, 2024

Anaheim, CA

 

Sapient will be participating in the Bruker eXceed Symposia at ASMS, including with a session in the Multiomics track.

 
 
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Q&A Corner: How can machine learning (ML) boost discovery potential?

Sapient’s Co-Founder and Head of Computational R&D Operations, Dr. Saumya Tiwari, shares how we leverage ML in data pre-processing as well as in downstream analysis to rapidly reveal patterns of interest in nontargeted multi-omics datasets. Click to listen.

 
 

PharmaShots Feature: “Shedding Light on Sapient’s Recently Launched Discovery Proteomics Services”

"To enable greater discovery in plasma proteomics, we had to address two significant bioanalytical hurdles: capturing plasma proteins as well as exosomal and membrane-bound proteins which may be key for early detection, and allowing for analysis of these extracted proteins and PTMs with greater speed."

Thank you to PharmaShots for this profile which highlights the revolutionary aspects of Sapient's high throughput mass spectrometry-based proteomics offering. Explore how the method is fulfilling market gaps and contributing to step-change efficiencies in preclinical and clinical drug development. 

 

Ready to discover more?

Sapient can help you gain the actionable knowledge needed to propel your drug development programs forward – faster and with more successful results. Let's discuss how.

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San Diego, CA 92121

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